High quality nucleic acids are essential for reliable next-generation sequencing results and accurate data analysis. Library prep kits can only provide reliable results if the input nucleic acid is of adequate quality and purity. The chemagic™ and NextPrep™ nucleic acid isolation kits deliver high yields of superior-quality nucleic acids from plasma, serum and urine, which are ideal for the construction of NGS libraries. These kits offer researchers the ability to cost effectively concentrate and analyze the limited cell free nucleic acids contained in various volumes of plasma or serum and cfDNA from urine which enables researchers to screen for biomarkers for liquid biopsies and other clinical research applications.
These sample prep solutions can also be easily automated, ensuring greater standardization and time savings. The quality of the DNA and small RNA isolated using these kits has been validated by preparation of Illumina® libraries followed by sequencing.