ENABLING HIV EPIDEMIOLOGY Simplifying HIV Variant Tracking with Low Throughput Automation "Lab A" is an epidemiology lab tracking variants of the human immunodeficiency virus (HIV). They collect samples from approximately 16 people a day, amplify the whole viral genome with specific primers and the amplicons obtained are sequenced. An amplicon-based approach for whole genome sequencing (WGS) facilitates the analysis of [...]
10 THINGS THAT CAN (AND DO) GO WRONG WITH MANUAL LIBRARY PREP How To Minimize Human Error in Low Throughput NGS Workflows There are many steps during library preparation where human error can be introduced. These errors can negatively impact the reliability and accuracy of sequencing data and waste valuable samples. In this post we describe a few [...]
We recently interviewed Sean Banks, Director, Business Development at Psomagen, to learn how they are leveraging the HIVE™ scRNAseq solution to complement their single cell analysis services. Learn how.
Analyzing circulating cell free DNA (ccfDNA) offers a non-invasive, dynamic window into the body’s physiological state and its use as a biomarker is gaining rapidly. However, multiple challenges remain with establishing its routine application. This is mainly due to its low levels, high rates of fragmentation, and preanalytical variabilities associated with sample collection, cfDNA extraction and quantification. Here, we go through some tips on how one can establish a reliable cfDNA workflow from plasma samples.
SURVEILLANCE PLANS ARE ESSENTIAL FOR PANDEMIC PREPAREDNESS AND PREVENTION The main lesson being learned from the COVID-19 pandemic is the importance of detecting cases early, following up on close contacts and preventing further disease spread for as long as possible. Other new and emerging diseases can affect us anywhere and at any time. The European Centre for Disease Prevention and [...]
Meeting IVDR Requirements and More with New CE-IVD chemagic™ Nucleic Acid Purification Kits | In vitro diagnostic (IVD) manufacturers have been busy bees in the past months, working intensively to meet the new European Union regulations known as the European In Vitro Diagnostic Medical Device Regulation (EU IVDR) that come into play 26th May 2022.
Incorporating Normalization Beads into your NGS Workflow | Normalization is the process by which NGS libraries of different concentrations are diluted to the same final concentration before pooling and sequencing.
The Human Cell Atlas – Expanding the Understanding of Human Health and Disease | The international Human Cell Atlas (HCA) consortium was established to increase our understanding of human health and disease using single cell genomics and spatial imaging technologies to map every cell type in the human body.