10 THINGS THAT CAN (AND DO) GO WRONG WITH MANUAL LIBRARY PREP How To Minimize Human Error in Low Throughput NGS Workflows There are many steps during library preparation where human error can be introduced. These errors can negatively impact the reliability and accuracy of sequencing data and [...]
Analyzing circulating cell free DNA (ccfDNA) offers a non-invasive, dynamic window into the body’s physiological state and its use as a biomarker is gaining rapidly. However, multiple challenges remain with establishing its routine application. This is mainly due to its low levels, high rates of fragmentation, and preanalytical variabilities associated with sample collection, cfDNA extraction and quantification. Here, we go through some tips on how one can establish a reliable cfDNA workflow from plasma samples.
WEBINAR | This on-demand webinar explores innovative, reliable workflows developed to propel the efficiency of your genomics-based agricultural research workflows.
Reduce Static Electricity on Liquid Handlers | Throughout dry winter periods the air humidity changes. This change can cause a buildup of static electricity in the air and on plastic liquid handling tips for automated liquid handlers.
Nucleic acid extraction lies at the beginning of almost every molecular biology-based workflow. Although the principle behind it is simple, when done poorly, it can have a significant impact on final experimental results. If working with patient samples, maintaining sample integrity becomes even more essential and reliable results are paramount to ensuring a fast and accurate diagnosis.
The laboratory workforce is shrinking making it more difficult to fill open positions. This lack of expertise will make automation a critical component of lab management in the future.
Automate sample prep for QSight® Triple Quadrupole LC/MS/MS analysis | Improve the efficiency of your LC-MS/MS by automating your QSight® Triple Quadrupole LC-MS/MS sample prep with the JANUS® G3 workstation.
Scale NGS Projects with the Sciclone® G3 NGSx Automated Liquid Handler | Listen to Dr. Renata Pellegrino, the Laboratory Director in the Center for Applied Genomics at the Children’s Hospital of Philadelphia, discuss how her team has combined Sciclone® technology and Twist® Bioscience’s target capture chemistry to optimize her next-generation sequencing (NGS) workflow.
Three Sciclone® G3 Workstation Automated Methods for Targeted Sequencing are Designated Illumina Qualified | Illumina analyzed multiple automated liquid handling methods to determine if they provided consistent, reproducible library prep when used with Thermo Fisher® AmpliSeq™ technology for Illumina® sequencing.
Automation for KAPA® HyperPlus™ Kits | The Sciclone® G3 NGSx iQ™ workstation (Figure 1) is specifically designed to automate the most complex Next Generation Sequencing (NGS) library construction workflows.
