Blog2019-05-20T20:16:18+00:00

APPLIED GENOMICS  |  BLOG

Automate your Twist® Human Core Exome Kit on the Sciclone® G3 NGSx Workstation!

Exome Sequencing using Rapid Automation Technology | Efficient library construction for Next Generation Sequencing (NGS) of human whole exome sequencing (WES) is fundamentally improved with the superior oligo prob design and performance of the Twist® Human Core Exome Kit. This kit enables increased uniformity and enables increased uniformity and deeper coverage of difficult regions while driving down the cost per sample.

September 12th, 2019|Categories: Liquid Handling, NGS|

Preventing Cross Contamination with Automated Walk-Away Library Prep

Contamination-Free, Worry-Free, Walk-Away Library Prep Automation | Automation of library preparation increases throughput, reduces labor costs, and eliminates many of the sources of human error. As most next generation sequencing (NGS) library preparation protocols include one or more polymerase chain reaction (PCR) steps, an on-deck thermal cycler is needed to achieve true walk-away automation.

August 26th, 2019|Categories: Lab Automation, Liquid Handling, NGS|

Automated Liquid Handling Evolution: An Overview

AUTOMATED LIQUID HANDLING EVOLUTION: AN OVERVIEW One of the first reported systems for liquid handling was described in 1875 by Thaddeus M. Stevens, a professor in Analytical Chemistry at the College of Physicians and Surgeons of Indiana. The device was designed to control the flux of water through a filter paper to wash a filtrate. Although relatively simple, the apparatus [...]

July 29th, 2019|Categories: Lab Automation, Liquid Handling|

Quantification of In Vivo Target Engagement

Using Microfluidic Activity-Based Protein Profiling | A recent study published in SLAS Technologies by Reardon, H. T., et al., used activity-based protein profiling (ABPP) to accurately measure drug–target interactions in vivo. The authors needed to accelerate the ABPP workflows and avoid imaging artifacts which make conventional gels challenging to quantify.

July 3rd, 2019|Categories: Drug Discovery, Protein Characterization|

Perspectives on Small RNA Sequencing

Challenges and Complications of Small RNA Library Prep | This webinar will address a range of methods for optimizing small RNA library preparation. Anitha Jayaprakash, co-founder of T-cell receptor sequencing firm Girihlet, will provide her perspectives on sequencing small RNAs and its utility in the study of various applications...

June 26th, 2019|Categories: NGS|

Soil Metagenomics

Comprehensive Workflow for Soil Metagenomics Analysis Using Shotgun Sequencing | This webinar will discuss a comprehensive end-to-end workflow for soil metagenomic shotgun sequencing that offers an unbiased alternative to amplicon-based approaches to assess the composition of culture-free microbial communities and predict functional profiles...

May 22nd, 2019|Categories: Metagenomics, NGS|